Publications of Eduardo D. Sontag jointly with R. Hegde
Articles in journal or book chapters
  1. R. Albert, B. DasGupta, R. Hegde, G.S. Sivanathan, A. Gitter, G. Gürsoy, P. Paul, and E.D. Sontag. A new computationally efficient measure of topological redundancy of biological and social networks. Physical Review E, 84:036117, 2011. [PDF]
    In this paper, we introduce a topological redundancy measure for labeled directed networks that is formal, computationally efficient and applicable to a variety of directed networks such as cellular signaling, metabolic and social interaction networks. We demonstrate the computational efficiency of our measure by computing its value and statistical significance on a number of biological and social networks with up to several thousands of nodes and edges. Our results suggest a number of interesting observations: (1) social networks are more redundant that their biological counterparts, (2) transcriptional networks are less redundant than signaling networks, (3) the topological redundancy of the C. elegans metabolic network is largely due to its inclusion of currency metabolites, and (4) the redundancy of signaling networks is highly (negatively) correlated with monotonicity of their dynamics.



This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.

Last modified: Wed Apr 17 19:59:02 2024
Author: sontag.

This document was translated from BibTEX by bibtex2html